The NCCN guidelines of genetic high-risk assessment for breast, ovarian, and pancreatic cancer state that no specific screening guidelines exist for melanoma, but general melanoma risk management with education regarding clinical signs, minimizing UV exposure, and annual full-body skin examination with the addition of an eye exam should be considered for both BRCA1 and BRCA2 mutation carriers with a pathogenic or likely pathogenic mutation [37]. The gene discussed is BRCA1; the disease is pancreatic neoplasm.