TNFRSF11A and neoplasm: Studies have shown that TNFRSF11(RANK) is expressed in a variety of tumor tissues, such as osteosarcoma [10, 11], chondrosarcoma [12], breast cancer [13], prostate cancer [14, 15], renal cancer [16], oral squamous cell carcinoma [17], lung cancer [18], thyroid cancer [19], and melanoma [20].