However, in line with this view, a recent paper by Blanco-Melo et al. highlighted an unbalanced inflammatory response characterized by a reduced IFN-I and -III response to SARS-CoV-2 coupled to elevated chemokines and high expression of IL-6 in cell and animal models of SARS-CoV-2 infection and in transcriptional and serum profiling of COVID-19 patients (28). Here, IL6 is linked to COVID-19.