Interestingly, low BDCA3+ (CD141+) DC signature is associated with poor prognosis in lung adenocarcinoma (LUAD), kidney renal papillary cell carcinoma (KIRP), kidney renal clear cell carcinoma (KIRC), liver hepatocellular carcinoma (LIHC), head and neck squamous cell carcinoma (HNSC), and skin cutaneous melanoma (SKCM) (Figure 1). This evidence concerns the gene THBD and head and neck squamous cell carcinoma.