CRP and familial Mediterranean fever: Although most of the FMF patients investigated in this cohort were well-controlled by continuous colchicine therapy (Table S1), homozygous M694V mutation carriers showed a significant increase of CRP [median 82.1 mg/L (range 1.3–112.5 mg/L), p < 0.05] compared to patients with other mutations or HCs (Table 1, Table S1).