In the TSC1 truncating mutation group and the control group, we find that some of the differentially expressed proteins have been reported to be associated with epilepsy, including NQO1 (26), MOCS2 (27), PRODH (28), DCX (29), UBA5 (30), SRP9 (31), ARFGEF2 (32), ATG12 (33), MTR (34), KCNA2 (35), ADAM23 (36), KCNAB2 (37), TSC1 (10), IDS (38), GTF2I (39), and so on. This evidence concerns the gene ADAM23 and epilepsy.