TSC1 and tuberous sclerosis: Compared to transcriptomic data (DEG) and proteomic data (DEP) of forebrains from 3 Tsc1/Emx1-Cre mice and 3 wild-type mice, transcriptomic data of cortical tubers from 4 TSC patients and 4 autopsy control tissues (GSE16969), and transcriptomic data of brain tissues from 3 TSC patients and 3 normal brain tissues (GSE62019) (44), there are 6 up- and 8 down-regulated proteins in our present study that overlap with these four databases (Table 4).