BTNL3 and inflammatory bowel disease: Consistent with the recent studies, the role of BTNL3 in the homing and maintenance of a semi-activated state on Vγ4 + γδ T cells in the human gut might be relevant for the onset of gut autoimmune diseases such as ulcerative colitis and inflammatory bowel disease (Lebrero-Fernandez et al., 2016; Blazquez et al., 2018).