KCNN4 and endometrial cancer: Evidence indicates that iberiotoxin inhibits cell proliferation, migration, and invasion in breast and endometrial cancer cell lines, due to its blocking effects on BK channels (Schickling et al., 2015; Li et al., 2018); while charybdotoxin, a known blocker of KCa3.1, KV1.3, and BK channels, inhibits proliferation and cell cycle progression in pancreatic and endometrial cancer cell lines (Jager et al., 2004; Schickling et al., 2015; Li et al., 2018).