Meanwhile, the numbers of potential target genes of hsa_circRNA_101138-hsa-miR-107 were also shown in the network, such as NEDD9 which was associated with AD genetically in Chinese (Xing et al., 2011) and GSKIP which functioned as anchoring proteins to strengthen the cAMP/PKA/Tau axis signaling during AD pathogenesis in CSF. The gene discussed is MAPT; the disease is Alzheimer disease.