The CCK-8 (Fig. 3d) and trypan blue assay (Fig. 3e) results showed that circRNA CDR1as overexpression rescued cell proliferation and viability in DDP-sensitive NSCLC cells treated with cisplatin, which were reversed by both overexpressing miR-641 and silencing HOXA9. The gene discussed is HOXA9; the disease is non-small cell lung carcinoma.