HOXA9 and non-small cell lung carcinoma: As expected, the results showed that upregulation of circRNA CDR1as increased cell proliferation, viability and colony formation abilities in DDP-sensitive NSCLC cells treated with high-dose DDP, which were abrogated by overexpressing miR-641 and downregulating HOXA9, implying that upregulated circRNA CDR1as increased DDP chemoresistance in DDP-sensitive NSCLC cells by targeting miR-641/HOXA9 axis.