DNA methylation data were then successfully generated for a total of 22 CpG sites located near ADCY5, CDKN2A, DUSP9, HHEX, HMGA2, KCNQ1, PPARG, SLC30A8, TCF7L2, and WFS1, all of which were found to be T2DM-risk SNPs. The gene discussed is TCF7L2; the disease is type 2 diabetes mellitus.