For example, NELFE and PTBP3, as a kind of RBP, promote the malignant growth and metastasis of HCC cells by regulating the binding of MYC and splice variants (NEAT1_1, NEAT1_2, and miR-612) to the target promoter and the stability of MYC-regulated mRNAs [46, 50]. The gene discussed is MYC; the disease is hepatocellular carcinoma.