The lack of association between myostatin protein expression and HbA1c in T1D suggests that (a) the involvement of myostatin in the development insulin resistance does not necessarily extend to an association with HbA1c, and/or (b) obesogenic factors that are often associated with T2D participants may be a key feature of the pathology that is driving a higher myostatin expression, as suggested by previous work in obese individuals (Amor et al., 2018; Hittel et al., 2009). Here, MSTN is linked to Insulin resistance.