Evidence in rodent models suggests that myostatin expression is elevated in type 1 diabetes (Chen, Cao, Ye, & Zhu, 2009) and elevated myostatin expression is associated with impaired insulin signaling/sensitivity (Brandt et al., 2012; Chen et al., 2009; Wang et al., 2012). The gene discussed is MSTN; the disease is type 1 diabetes mellitus.