Derangement in leptin/adiponectin axis, which is characterized by increased leptin/adiponectin ratio in these conditions might predispose affected individuals to vascular inflammation and therefore the progression of micro‐ and macrovascular complications of diabetes (Katsiki, Mikhailidis, & Banach, 2018; Liang & Ye, 2019; Lim et al., 2015; López‐Jaramillo et al., 2014; Nosalski & Guzik, 2017; Rodríguez, Nunes, Mastronardi, Neeman, & Paz‐Filho, 2016). The gene discussed is ADIPOQ; the disease is diabetes mellitus.