In conclusion, in our study the rs8180209 variant of SNCA, the rs2270968 variant of MCCC1, the rs7479949 variant of DLG2, the rs10748818 variant of GBF1 and the rs4771268 variant of MBNL2 were found to be associated with the susceptibility to PD in the southern Chinese population. This evidence concerns the gene DLG2 and Parkinson disease.