As expected from previous studies involving senolytics and tumor cells [15, 27, 37], ABT‐263 exerts its effects against senescent tumor cells by inducing apoptotic cell death, as demonstrated by the increase in Annexin‐V/PI staining and the apoptosis markers cleaved PARP and cleaved caspase‐3 (Fig. 3A–D). Here, ANXA5 is linked to neoplasm.