Sex differences are also observed in several animal models of hypertension, including the angiotensin II‐infusion model in mice and rats, the Dahl S rat, and the L‐NAME rat infusion model (Hinojosa‐Laborde, Lange, & Haywood, 2000; Ouchi, Share, Crofton, Iitake, & Brooks, 1987; Pollow et al., 2014; Sainz et al., 2004; Xue et al., 2009; Xue, Pamidimukkala, & Hay, 2005). The gene discussed is AGT; the disease is hypertensive disorder.