Although the precise genetic determinants are not yet known, a genome‐wide association study (GWAS) revealed several loci on chromosomes 2, 5, 7, 8, and 16 showing significant associations with melanoma occurrence and progression, and comparison to human melanoma GWAS results indicated shared association signals at CDKAL1 and TERT loci as well as the proximal CCND1, FTO, PLA2G6, and TMEM38B‐RAD23B loci [90]. This evidence concerns the gene PLA2G6 and melanoma.