KRT18 and heart failure: Using a specific ELISA (Fig. 1b), we interestingly found that heart failure patients receiving amiodarone revealed significantly higher serum levels of caspase-cleaved K18 (n = 6; 293.6 ± 58.4 U/L) compared to patients without amiodarone therapy (n = 9; 172.1 ± 17.9 U/L) or healthy control individuals (n = 13; 174.8 ± 14.0 U/L).