Combining the compound-putative target network with the PPI network of hepatitis B targets, a total of 13 potential targets were obtained, namely, CDK2, TLR9, GPT, NOD2, EHMT2, STAT3, JUN, BRCA1, TP53, CCNB2, TNF, CREB1 and CDK6. The gene discussed is TLR9; the disease is hepatitis B virus infection.