Specifically, low expression of LINC01133 suppressed the proliferation and metastasis of GC cells via regulating APC expressions and Wnt/β-catenin signals11; lncRNA GMAN was related to the metastasis of GC and could promote ephrin A1 translation via competitively binding to GMAN-AS12; and lncRNA HOXC-AS3 could promote the occurrence of GC via regulating HDAC5 at transcriptional level13. The gene discussed is HDAC5; the disease is gastric cancer.