Moreover, LINC01446 was confirmed to downregulate the Ras-related dexamethasone-induced 1 (RASD1) expression at transcriptional level through recruiting the activated histone lysine-specific demethylase LSD1 to the promoter area of RASD1, thereby accelerating the proliferation and metastasis of GC cells. The gene discussed is LINC01446; the disease is gastric cancer.