For this assay, single cells were isolated from two groups of matched MPNST tumors: (1) p53m/m,nf1b−/−,nf1a+/−, suz12-mutant MPNSTs and (2) p53m/m, nf1b−/−, nf1a+/−, suz12-wild-type MPNSTs. Here, SUZ12 is linked to malignant peripheral nerve sheath tumor.