Moreover, keratinocytes are rekated to cell apoptosis in psoriasis [17], and inhibition of cell apoptosis contribute to the amelioration of psoriasis (MiR-20a-3p regulates TGF-β1/Survivin pathway to affect keratinocytes proliferation and apoptosis by targeting SFMBT1 in vitro). This evidence concerns the gene SFMBT1 and psoriasis.