In addition, 96 GC patients were tested for H. pylori infection (30 cases in the H. pylori-positive group, 66 cases in the H. pylori-negative group), and we found that BATF2 and METTL3 IHC expression in the two groups was not significantly different (Additional file 11: Figure S6A). The gene discussed is BATF2; the disease is gastric cancer.