HOTAIR and MET gene expression showed a remarkable tendency of reverse regulation in adrenocortical carcinoma, cervical squamous cell carcinoma and endocervical adenocarcinoma, lymphoid neoplasm diffuse large b-cell lymphoma, glioblastoma multiforme, head and neck squamous cell carcinoma, kidney renal clear cell carcinoma, acute myeloid leukemia, liver hepatocellular carcinoma, lung adenocarcinoma and uveal melanoma (Fig. 8e). The gene discussed is HOTAIR; the disease is head and neck squamous cell carcinoma.