In summary, the current research suggested that miR-1908-3p might promote the breast cancer cells proliferation and metastasis by suppressing eight genes (ID4, LTBP4, GPM6B, RGMA, EFCAB1, ALX4, OSR1 and PPARA) and the serum level of miR-1908-3p could be used as a diagnostic and predictive biomarker for breast cancer. Here, ALX4 is linked to breast cancer.