NPSR1 and attention deficit-hyperactivity disorder: Despite some inconsistency of the studies linking OXTR rs53576 variant with impaired socioemotional traits and behavior [150], the rs53576 and rs2254298 OXTR single nucleotide polymorphisms were shown to correlate with increased severity of social deficits in ASD, and less with social deficit in ADHD, thus indicating a differential relationship between this neuropeptide receptor gene allele and the social phenotype [80].