NLRP3 and type 2 diabetes mellitus: In this context, salvianolic acid A from Salvia miltiorrhiza Bunge was also able to alleviate atherosclerosis and type 2 diabetes in male Zucker diabetic rats on high fat diets, by decreasing hemoglobin A1C and C-reactive protein levels, improving lipid profile and aortic tissue condition, through the inhibition of NLRP3 inflammasome and NF-ϏB signaling activation [100].