In this study, we explored the therapeutic potential of SP-2577 (Seclidemstat), a potent reversible LSD1 inhibitor currently in Phase I clinical trials for Ewing Sarcoma (NCT03600649) and for advanced solid tumors (NCT03895684), to promote anti-tumor immunity and T-cell infiltration in SWI/SNF-mutant OC. Here, KDM1A is linked to neoplasm.