ACE and Hypertension: Pharmacological agents such as angiotensin converting enzyme inhibitors, statins, and angiotensin receptor blockers have been demonstrated to decrease arterial stiffness in hypertension and end‐stage renal disease.41, 42, 43, 68 These decreases are hypothesized to be attributed to decreased levels of oxidative stress and inflammatory cytokine production, enhanced nitric oxide bioavailability, and decreased blood pressure.