Current limitations of the commercially available homologous allergens Pol d 5 and Ves v5 to distinguish between YJV and PDV allergy in double-positive patients by CRD were demonstrated by the fact that a good accordance between Ag5-based CRD and CAP-inhibition assays can only be achieved when the value of sIgE in kUA/L to Ves v 5 is about twice of those to Pol d 5 and vice versa [71, 72]. This evidence concerns the gene CAP1 and Allergy.