Nonclassical congenital adrenal hyperplasia due to 21-hydroxylase deficiency (NC-CAH) is caused by mutations in the active 21-hydroxylase gene (CYP21A2) and is the most common congenital disorder of steroid biosynthesis of the adrenal gland, with an estimated prevalence of 1:200–1:1000 in the Caucasian population [1, 2]. Here, CYP21A2 is linked to congenital adrenal hyperplasia.