All cell lines analyzed, namely the lung cancer cell lines H1299 (Fig. 3B) and A549 (Fig. 3C), the human embryonic kidney cell line HEK293 (Fig. 3D), the human cervical carcinoma cell line HeLa (Fig. 3E) and the human breast cancer cell line MDA MB 231 (Fig. 3F) showed an enhanced phosphorylation of SRC-3 at S857 upon exposure to the three p38MAPK activators. The gene discussed is NCOA3; the disease is breast cancer.