HCMV infects a broad range of target tissues in humans, including epithelia of the oropharynx, endothelia, fibroblasts and resident macrophages11–16; infection begins with the virus attaching to host cell receptors, including epidermal growth factor receptor (EGFR), platelet-derived growth factor receptor alpha (PGFRα), or integrin17–19. This evidence concerns the gene EGFR and infection.