Therefore, psoriasis provides a model to characterize associations between inflammation, dyslipidemia and early coronary artery disease before cardiovascular events.[55,60, 61, 62, 63, 64] In that context, our study demonstrated that the product of chronic inflammatory cytokines in the form of IFNγ/TNFα associated with non-calcified coronary burden beyond traditional risk factors. The gene discussed is IFNG; the disease is metabolic syndrome.