SLC5A2 and type 2 diabetes mellitus: Clinical trials in patients with type 2 diabetes mellitus (T2DM) showed that SGLT2 inhibitors, such as empagliflozin and canagliflozin, significantly reduced the primary outcome, a composite of death from CV causes, nonfatal myocardial infarction, and nonfatal stroke, compared to that of placebo [6, 7].