A nephrotic syndrome was diagnosed (serum albumin 2.5 g/dL, proteinuria 9.6 g/24 h), with a rise in serum creatinine (1.17 mg/dL), active urinary sediment (red blood cells (RBC) 27/mm3, white blood cells (WBC) 60/mm3), and non-regenerative anemia (hemoglobin 10.7 g/dL, reticulocytes 35 G/L). The gene discussed is ALB; the disease is anemia.