The renal pathological results of these 8 patients with both IgG and IgM antibodies were: acute kidney tubular necrosis in 2, minimal change disease in 1, class III lupus nephritis in 1, MPGN with a “full-house” pattern of endo-membranous deposits in 1 (lupus-like GN without lupus auto-antibodies), pauci-immune crescentic GN in 1, hypertensive nephropathy in 1, acute interstitial nephritis with lymphocytic infiltration in 1. The gene discussed is CD40LG; the disease is primary membranoproliferative glomerulonephritis.