The patient’s age, occupation, and the ratio of positive to total SLNs were found to be strongly associated with ALN metastasis (P < 0.05), whereas ALN metastasis was not associated with the delay in diagnosis, tumor primary site, tumor location, tumor size, pathological type, ER status, PR status, Her-2 status, triple negative status, Ki-67 status, tumor grade, or postoperative ALNs (P > 0.05). Here, ESR1 is linked to neoplasm.