The two groups exhibited significant differences in age distribution, Her-2 status, and ratio of positive to total SLNs (P < 0.05), whereas the remaining characteristics including delay in diagnosis, tumor primary site, tumor location, tumor size, pathological type, ER status, PR status, triple negative status, Ki-67 status, tumor grade, and postoperative ALNs were not significantly different between the two groups (P > 0.05). Here, ESR1 is linked to neoplasm.