LPA and Stroke: The findings of these meta-analyses demonstrate a 70% increased risk of CHD in subjects in the top vs. the bottom tertile of Lp(a) [27], a persistent independent and continuous association of Lp(a) with the risk of future CHD after adjusting for established risk factors [28] and a continuous association of Lp(a) level with the risks of CHD and stroke independent of traditional risk factors [29].