Blanco-Melo et al., also found a high level of chemokines induction, in concordance with our data, as well as high levels of type I and type III interferon response in human adenocarcinoma alveolar basal epithelial (A549) cells expressing ACE2, and in Calu-3 host cells infected with SARS-CoV-2 [32]. This evidence concerns the gene ACE2 and adenocarcinoma.