SOAT1 and dementia: Besides using their database to identify drugs that can up-/downregulate MERCs resident proteins (e.g., according to their database, the compound rivastigmine, used to treat different types of dementia including AD, can upregulate MFN2 and downregulate sterol O-acyltransferase 1, (SOAT1) [135]), it will be possible to identify the different signaling pathways induced by these compounds.