In another very interesting approach, sterically stabilized nanodisks based on high-density lipoproteins (HDL) carried MPL, CpG (ligand of Toll-like receptor-9), and antigen for personalized cancer immunotherapy; synthetic high-density lipoprotein (sHDL) nanodisks were composed of phospholipids and apolipoprotein A1 (ApoA1)-mimetic peptides (the peptides were named 22A because they were synthesized as 22-mer peptides, derived from the repeat α-helix domain of ApoA1) [102]. This evidence concerns the gene APOA1 and cancer.