WNK4 and acute respiratory distress syndrome: The levels of WNK4 (Figure 6D) and SPAK (Figure 6E) were higher in rats of ALI and ALI + HG (p < 0.05, comparing the sham group) and were decreased in the rats of ALI receiving pre-treatment of post-ALI treatment of the NKCC1 inhibitor (p < 0.05, comparing the ALI group).