The incidence of basophil non-responders in our cancer patient cohort is similar to that described in other groups of patients whose basophils were subjected to IgE-mediated stimulation using the BAT [9,10], for example, in children evaluated for peanut allergy [13], tree and grass pollen allergies [8], and cow’s milk intolerance [71]. The gene discussed is IGHE; the disease is cancer.