APP and Alzheimer disease: Considering miRNAs previously suggested to relate Alzheimer’s Disease, Masoud et al. discovered, from various growth stages, that the expression of miR-106b (binding APP mRNA) was transiently stimulated, and a similar tendency was observed regarding miR-29, a molecule targeting SP1. In addition, miR-29b and miR-132, which were deregulated in AD samples, displayed a profound elevation in a short exposure period [102].