TNF and infection: Although no evidences supporting a role for SLC39A7 in regulating expressions of TNF-α, IL-6, and IL-10 in a fashion reversible by zinc supplementation were found (Fig 5A), secretion of TNF-α and IL-6 proteins at 48h after BCG-p infection were reduced in SLC39A7-knockdown cells than in control cell and this reduction in secretion of TNF-α and IL-6 was reversible by zinc supplementation (Fig 5B).