However, the mean levels of PCSK9 in patients with grade 0, 1, or 2 dengue on illness days 4–6 after illness onset were 46.11 ng/mL, 95.76 ng/mL, and 145.8 ng/mL, respectively, indicating elevated PCSK9 levels in patients with more severe disease (Figure 5B). Here, PCSK9 is linked to dengue disease.