Furthermore, ROC curve analysis showed that the survival model composed of ANGPT2, EMCN, GLDN, USHBP1 and ZNF532 showed good predictive value for survival when analyzed at 12 months (area under the curve (AUC)=0.713), 36 months (AUC=0.622), and at 60 months (AUC=0.751) for the HCC patients (Figure 5B). This evidence concerns the gene GLDN and hepatocellular carcinoma.