Although these cells secrete albumin (Jeon & Kim, 2011), due to being hepatoma derived, they show characteristics of dedifferentiation from mature hepatocytes: Huh7 cells express tumor markers and have limited expression of CYP enzymes, hepatic transcription factors, and nuclear receptors (Godoy et al., 2013). The gene discussed is PPIG; the disease is hepatocellular carcinoma.