According to KEGG pathway analysis (Fig. 5d), copositive correlation genes were enriched in “pertussis,” “Staphylococcus aureus infection,” “lysosome,” “cell cycle,” and “glycosaminoglycan biosynthesis chondroitin sulfate/dermatan sulfate” and conegative correlation genes were enriched in “oxytocin signaling pathway,” “phosphatidylinositol signaling system”, “adrenergic signaling in cardiomyocytes,” “retrograde endocannabinoid signaling,” and “cholinergic synapse.” The gene discussed is OXT; the disease is staphylococcus aureus infection.